Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine and pancreatic cancer Effects of hydroxychloroquine on taste Our Plaquenil hydroxychloroquine Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. An overdose of hydroxychloroquine can be fatal, especially in children. Plaquenil overdose must be treated quickly. You may be told to induce vomiting right away at home, before transport to an emergency room. Ask the poison control center how to induce vomiting in the case of an overdose. We report a case presenting with massive overdose of hydroxychloroquine who survived without any sequelae. A 17‐year‐old girl presented to the Emergency Department 45 min after the ingestion of 22 g of hydroxychloroquine in a suicide attempt. We believe this is highest dose yet reported in the medical literature. The patient developed hypotension, life‐threatening ventricular arrhythmias. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Massive hydroxychloroquine overdose Hydroxychloroquine Oral Uses, Side Effects, Interactions., Plaquenil Uses, Dosage & Side Effects - Chloroquine physical properties We report a case presenting with massive overdose of hydroxychloroquine who survived without any sequelae. A 17-year-old girl presented to the Emergency Department 45 min after the ingestion of 22 g of hydroxychloroquine in a suicide attempt. We believe this is highest dose yet reported in the medical literature. Massive hydroxychloroquine overdose.. Massive hydroxychloroquine overdose, Acta.. Hydroxychloroquine, a potentially lethal drug Medicina.. Commonly used on holidays in malaria prone destinations, chloroquine and hydroxychloroquine will not be over familiar to the emergency physician. However, it is one of the leading causes of drug overdose in malaria prone countries and also the occasional toddler has managed to consume the grandparents lupus or rheumatoid arthritis medication leading to lethal consequences. A 17 year old girl, believed to have ingested an overdose of her mother's medication, was found comatose and died after several hours of resuscitative efforts; she had hydroxychloroquine concentrations of 7.5 mg/L in antemortem blood, 20 mg/L in postmortem heart blood and 220 mg/kg in liver Treacy, 1999. Hydroxychloroquine overdoses are rarely reported despite the frequent use of this drug. A literature search found only 7 acute overdose reports in the English medical literature.2, 3, 4, 5, 6, 7, 8. The lethal dose is not well established.