Whats the dosage that causes plaquenil toxicity

Discussion in 'Plaquenil 200mg' started by 100p, 16-Mar-2020.

  1. WhiteShaman Guest

    Whats the dosage that causes plaquenil toxicity


    One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus.

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    I normally post on the arthritis board, and due to toxicity of the Plaquenil after 2 years, I have had to discontinue it, since I failed the visual field testing. Although I take Enbrel, and MTX, neither one work as well as the Plaquenil and the fatigue and joint pain have returned full force. Plaquenil can produce pigment changes in the macula of the retina. The retina is the part of the back of the eye that you see with. The macula is the central part of the retina responsible for central fine vision. With Plaquenil related toxicity, the pigment in the macula can change and alter vision by producing blurring and distortion of objects. A cumulative dose of 1000g of hydroxychloroquine or 460g of chloroquine was likely the largest risk factor, which was typically achieved after 5-7 years of a typical dosage 8, 10. However, there have been case reports of patients with hydroxychloroquine toxicity as early as 1.9 months after starting treatment 11.

    It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress.

    Whats the dosage that causes plaquenil toxicity

    Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Conditions Plaquenil-related Eye Problems Eugene Eye Care

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  7. Dr. Fraunfelder “One of the main rules, but not a hard rule, is if it’s a drug toxicity, it usually is bilateral.” Dr. Fung “I’m always concerned that the prescribing doctors are not completely aware of the dose-related toxicity of chloroquine and hydroxychloroquine. So I always check and calculate the dose.

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    Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Aug 28, 2015 Plaquenil toxicity and lowering dosage Posted on August 28, 2015 by Luke — No Comments ↓ Plaquenil generic name hydroxychloroquine is one of the few medications that is regularly prescribed for Sjogren’s Syndrome, despite the fact that it has not been approved for SS by the FDA, so any use is off-label.

     
  8. Bocr Moderator

    Plaquenil, hydroxychloroquine (HCQ), is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and other inflammatory and autoimmune diseases. Plaquenil/Hydroxychloroquine - which eye tests do. Conditions Plaquenil-related Eye Problems Eugene Eye Care Plaquenil and Eye Exams Arthritis Information
     
  9. Avka Well-Known Member

    Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). Taking Plaquenil for Rheumatoid Arthritis Treatments for Rheumatoid Arthritis Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
  10. Riddick_+ XenForo Moderator

    Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Feb 19, 2020 The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days.

    Hydroxychloroquine Oral Uses, Side Effects, Interactions.