At first it seemed like it helped now I feel the same as before I started taking the medicine other than the fact that none of my clothes fit and there is a lot more of me to carry around. Anyone know if I quit taking it if the weight will fall back off I started Hydroxychloroquine 2 weeks ago. One week in and I thought this may just work, except for the ‘extra itchiness’ I seemed to get every night. Chloroquin family Plaquenil and prednisone for rheumatoid arthritis Hydroxychloroquine lung disease Plaquenil can cause loss of appetite and I agree that losing weight at this rate and suffering diarrhea is not healthy and might mean you become ill nourished and dehydrated. I suggest lowering the dose, going back to the original, until your tum has settled down then very gradually increasing it to give your body the maximum chance to adjust. Plaquenil comes in 200 milligram mg tablets that are taken by mouth. To prevent malaria in adults, two tablets are typically taken once a week, on the same day each week. Plaquenil and weight loss. Hollywood8687 02/27/2014. I recently went on Plaquenil a few months ago, and I have been noticing how much weight I've been losing. I feel like I am losing too much weight. I am a thin person, and I am sick very often. Last week, I lost three pounds, and the week before I lost two pounds. I was prescribed this drug to ease my ra disease, I was taking 400mg per day which was to last for 3 months then reduced to 200mg. Right before I hit the two week mark, I woke up with my heart racing and continued feeling my heart flutter all day and I just felt week and tired. After msging Rheum, decided to stop taking meds to see how I feel and continue with the AIP to handle symptoms and try to work at ‘healing from inside out! Time will tell and I’m eager to see how much the AIP is helping once odd meds. Average weight loss on plaquenil Plaquenil oral Reviews and User Ratings Effectiveness., Plaquenil Hydroxychloroquine - Side Effects, Dosage. What is plaquenilChemical structure of chloroquinePlaquenil changed your hairWhat does plaquenil do to your eyesight Plaquenil has been the one and only drug I've taken, but aside from weight gain, I was getting migraines that made me feel like I was dying, my vision was immediately affected blurry, photosensitive, my gums were bleeding, I was dizzy all the time and always has a terrible sore throat - not to mention the nightmares from Hell every night. Plaquenil and weight gain -. Plaquenil and weight loss DailyStrength. Weight gain while on Plaquenil? lupus. Severe and irreversible retinal damage has been reported with the use of hydroxychloroquine. Risk factors for retinal damage include daily doses more than 6.5 mg/kg 5 mg/kg base of actual body weight, durations of use greater than 5 years, subnormal glomerular filtration, use of concomitant drugs such as tamoxifen, and concurrent macular disease. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.