Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil trackid sp-006 Drug information about chloroquine Which is more effective methotrexate or plaquenil Average cost for 30 tablets of plaquenil G chloroquine phosphate 600 mg base orally once a day for 2 days, followed by 500 mg chloroquine phosphate 300 mg base orally once a day for at least 2 to 3 weeks Comments-Treatment is usually combined with an effective intestinal amebicide. Approved indication For the treatment of extraintestinal amebiasis. Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Solubility Choroquine Phosphate Chloroquine phosphate is freely soluble in water.3,5,6 An aqueous solubility of 1 in 4 was reported.7 It is not clear if this means 1 part dissolved in 4 part solution, i.e. 250 mg/ml, or 1 part dissolvable in 4 parts of water, i.e. 200 mg/ ml. Other workers reported a solubility of 100 mg/ ml in water.8. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine phosphate solubility Chloroquine Phosphate - Antirheumatic Agents, Antimalarials., Chloroquine phosphate C18H32ClN3O8P2 - PubChem Hydroxychloroquine memesPlaquenil reportChloroquine phosphate and pregnancy Solubility. Show More. C6628 Chloroquine diphosphate salt, powder or crystals, 98.5-101.0% dry basis, Sorry we cannot compare more than 4 products at a time. Chloroquine diphosphate salt Sigma-Aldrich. Biowaiver monographs for immediate release solid oral dosage.. Chloroquine - FDA prescribing information, side effects and uses. CHLOROQUINE PHOSPHATE, USP. For Malaria and Extraintestinal Amebiasis. DESCRIPTION. ARALEN, chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. ARALEN is an antimalarial and amebicidal drug. Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine was granted FDA Approval on 31 October 1949. Chloroquine phosphate Drug Entry Chloroquine. Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. 4 It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. 17. Chloroquine was granted FDA Approval on 31 October.