Additionally, another exception occurred while executing the custom error page for the first exception. Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Can plaquenil lower your immune system Compare sulfasalazine to plaquenil This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. In addition to retinal thinning and outer retinal degeneration, HCQ appears to induce choroidal thinning, particularly at the level of the choriocapillaris. These findings will broaden our understanding on ocular toxicity of HCQ and clinical evaluation for the toxicity. Ocular findings of HCQ retinal toxicity as detected by various screening modalities. A female patient was diagnosed with HCQ retinal toxicity at the age of 53 years, having taken HCQ for 12 years at 400 mg/day. She was not obese and had no additional risk factors for toxicity. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Retinal thinning in plaquenil toxicity Retinal toxicity associated with chronic exposure to., Choroidal Thinning Associated With Hydroxychloroquine Retinopathy. Plaquenil ful lfiel derg severeKeflex and plaquenilPlaquenil help paying The main outcomes were toxicity as determined by characteristic visual field loss or retinal thinning and photoreceptor damage. They also examined risk factors and prevalence. The study findings revealed that when hydroxychloroquine was used at doses 5mg /kg, the risk of retinopathy was 1% in the first 5 yrs. 2% in 10 yrs. 20 % after 20 yrs. My Take on New Ocular Screening Guidelines for Plaquenil.. Hydroxychloroquine-related retinal toxicity Rheumatology Oxford.. Has anyone had retinal damage from Plaquenil? - Lupus - Inspire. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some. Ocular Surgery News The American Academy of Ophthalmology has published several dosing and screening recommendations for hydroxychloroquine to avoid potential retinal toxicity, yet some patients. Although it is considered rare, retinal toxicity from the intake of Plaquenil can be irreversible even if the drug is discontinued 2, 3. What is Plaquenil Toxicity? The toxicity resulting from the intake of Plaquenil is due to its affinity for melanin-containing structures in the body.