Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine and liver cirrhosis Chloroquine synthetic Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation. Plaquenil What You Need to Know. Contents What is Plaquenil. Reduce muscle and joint pain; Reduce lupus related rashes; Protect against pleuritis inflammation of the lining of the lungs. of generic hydroxychloroquine can sometimes cause stomach irritation that usually does not occur with the brand name Plaquenil. Your doctor can make. Yes, plaquenil is difficult to adjust first, but after the first year of treatment and side effects, the benefits outweigh the problems. So, stick with it. In my opinion, the plaque nil is keeping the immune system regulated and the pain and other symptoms described will reduce. Lupus is not an illness without pain or sacrifice, but, it’s. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Does plaquenil reduce pain How Does Plaquenil Work For Rheumatoid Arthritis, Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Can plaquenil help with fatiguePlaquenil pill pictureLichen planus chloroquine I have been on Plaquenil for years. It has not helped me with fatigue. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time. I also take Tramadol for pain and now Indomethicin has been added to the mix to help with stiffness. Plaquenil for fatigue and pain DailyStrength. Plaquenil side effects - kidney problems? - Symptoms.. Will you have Back pain with Plaquenil - eHealthMe. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats; very slow heart rate, weak.