Chloroquine hydrochloric acid

Discussion in 'Hydroxychloroquine' started by Gruzilkin, 26-Feb-2020.

  1. glad2k Well-Known Member

    Chloroquine hydrochloric acid


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Quantum chemical techniques to investigate the inhibitory action of chloroquine for aluminium in hydrochloric acid. Experimental Materials The aluminium sheets used in this study were obtained from KOLORKOTE, Sango-Ota, Nigeria and have the following composition wt% Si 0.125, Mn 0.0158, Oct 29, 2013 Observations How do we know a chemical reaction is taking place? What gas is produced and how do we know? What are the other two products when a metal carbonate reacts with an acid? Chloroquine Hydrochloride is the hydrochloride salt of chloroquine, a synthetic quinoline with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine hydrochloric acid

    JDI 025 004 R1 525. - Taylor & Francis, Calcium Carbonate and Hydrochloric Acid Demo - YouTube

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  6. MULTIPARTICULATE ENTERIC COATED FORMULATION OF CHLOROQUINE PHOSPHATE FOR BETTER PATIENT COMPLIANCE. MULTIPARTICULATE ENTERIC COATED FORMULATION. 750 mL of 0.1 N hydrochloric acid was used.

    • MULTIPARTICULATE ENTERIC COATED FORMULATION OF CHLOROQUINE..
    • Chloroquine hydrochloride C18H28Cl3N3 - PubChem.
    • Pharmacokinetics of Chloroquine and Metronidazole in Rats.

    Structure, properties, spectra, suppliers and links for Chloroquine Hydrochloride, 3545-67-3. Chloroquine enters the red blood cell, inhibiting the parasite cell and digestive vacuole by simple diffusion. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. This agent may also interfere with the biosynthesis of nucleic acids.

     
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