Prophylaxis for international travel to chloroquine resistant area

Discussion in 'Health Canada Drug Database' started by Mixator, 19-Mar-2020.

  1. Neram User

    Prophylaxis for international travel to chloroquine resistant area


    Updated information reflecting changes since publication can be found in the online version of this book (gov/yellowbook) and on the CDC Travelers’ Health website (gov/travel). The information was accurate at the time of publication; however, this information is subject to change at any time as a result of changes in disease transmission or, in the case of YF, changing country entry requirements.

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    Apr 15, 2002 Chloroquine is the drug of choice for people who travel to these areas; however, resistance to chloroquine is now widespread in all areas of the world where malaria is endemic, but it is still an effective choice for prophylaxis in travelers to Mexico, the Caribbean, Central America, Argentina. Malaria Information and Prophylaxis by Country; Country Areas with Malaria Drug Resistance 2 Malaria Species 3 Recommended Chemoprophylaxis 4 Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries; Democratic Republic of the Congo Congo-Kinshasa All Chloroquine P. falciparum 90%, P. ovale 5%, P. vivax rare Mefloquine may be appropriate for long-term prophylaxis in chloroquine-resistant areas because of its convenient weekly dosing, but concern has increased regarding its neuropsychiatric side-effect profile, especially with the Food and Drug Administration label indicating that neurologic side effects may persist.

    Arguin (Malaria) The following pages present country-specific information on yellow fever (YF) vaccine require­ments and recommendations (Table 2-06) and malaria transmission information and prophy­laxis recommendations. Country-specific maps of malaria transmission areas, country-specific maps depicting yellow fever vaccine recommen­dations, and a reference map of China are included to aid in interpreting the information.

    Prophylaxis for international travel to chloroquine resistant area

    Need for Malaria Prophylaxis by Travelers to Areas With., Malaria Information and Prophylaxis, by Country D - CDC

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  7. In areas with chloroquine-resistant Plasmodium falciparum, travelers will need to take atovaquone/proguanil, doxycycline, or primaquine 1 day before entering the area, or mefloquine 2 to 7 weeks before travel SOR B, based on prospective patient-oriented outcomes and expert opinion.

    • When should travelers begin malaria prophylaxis? MDedge..
    • Long-Term Travelers & Expatriates - Chapter 9 - 2020 Yellow Book..
    • Long-Term Malaria Prophylaxis for Travelers - Medscape.

    An alternative to chloroquine for prophylaxis only in areas with chloroquine-sensitive malaria 310 mg base 400 mg salt orally, once/week 5 mg/kg base 6.5 mg/kg salt orally, once/week, up to a maximum adult dose of 310 mg base Begin 1–2 weeks before travel to malarious areas. Areas with Malaria Drug Resistance 2 Malaria Species 3 Recommended Chemoprophylaxis 4 Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries; Gabon All Chloroquine P. falciparum 90%, P. malariae, P. ovale, P. vivax 10% combined. Atovaquone-proguanil, doxycycline, mefloquine, or tafenoquine 6 Gambia, The All Chloroquine P. falciparum ≥ 85%, Jul 23, 2014 Chloroquine is used for the prophylaxis of malaria in areas of the world where the risk of chloroquine-resistant falciparum malaria is still low. It is also used with proguanil when chloroquine-resistant falciparum malaria is present. However, this combination may not be ideal.

     
  8. way XenForo Moderator

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  9. lepres User

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