Although their therapeutic and toxic doses differ, they are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity. The image below depicts hydroxychloroquine retinopathy. Fluorescein angiogram of left macula in patient with hydroxychloroquine retinopathy. Chloroquine vs chloroquinine Rheumatoid factor dropped plaquenil Chloroquine and proguanil during pregnancy What is the drug of choice for acute attacks of malaria caused by chloroquine-sensitive strains of P. falciparum and P. vivax? Chloroquine Does chloroquine have a large or small Vd? Like chloroquine, the drugs amodiaquine and hydroxychloroquine belong to a class of quinine analogues called 4-aminoquinolines. 8-aminoquinolines. Pamaquine, primaquine, and tafenoquine are antimalarial drugs that belong to a family named 8-aminoquinolines. Pamaquine is closely related to primaquine. Compared to primaquine, pamaquine is more. Rapamycin belongs to the class of macrocyclic immunosuppressive drugs used in preventing rejection after organ transplantation, topical treatment of facial angiofibromas, renal angiomyolipoma, brain tumors associated with tuberous sclerosis and chemotherapy for a variety of cancers. Retinopathy may be asymptomatic or may cause central or paracentral scotomas leading to difficulty reading or performing fine visual tasks (due to parafoveal metamorphopsia). Reprinted from American Journal of Ophthalmology, Vol 104, Johnson and Vine, Hydroxychloroquine therapy in massive total doses without retinal toxicity, pages 139-144, Copyright 1987, with permission from Elsevier Science. What family of drugs does chloroquine belong to Mechanisms of action of hydroxychloroquine and chloroquine., Medicinal Chemistry of Antimalarial Drugs - PharmaFactz Hydroxychloroquine and slurred speechChloroquine eye damage Chloroquine is an anti-malaria medicine that works by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine Uses, Side Effects & Warnings -. Rapamycin and Chloroquine The In Vitro and In Vivo Effects of.. Chloroquine - Malaria Home Page. Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria and to prevent malaria in areas or regions where chloroquine is known not to work resistance. Chloroquine may also cause itching in some people. All medicines may have some side effects. Minor side effects such as nausea, occasional vomiting, or diarrhea usually do not require stopping the antimalarial drug. If you cannot tolerate your antimalarial drug, see your health care provider; other antimalarial drugs are available. The drug, chloroquine, is a medication used to prevent and to treat malaria, as well as a type of liver infection. It was first used to treat malaria in 1944.