It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Chloroquine hydrochloride injection Sarafen and plaquenil Cellcept prednisone and plaquenil for rheumatoid arthritis Nervousness, irritability, dizziness although these effects are uncommon Major neurological side effects confusion, seizures – These are quite rare, but if you experience them, alert your doctor immediately. Exacerbation of psoriasis – If you have psoriasis, Plaquenil may make your condition worse. Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Serious side effects of plaquenil Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Plaquenil Hydroxychloroquine - Side Effects, Dosage. Plaquenil and msHow does plaquenil cause blindnessFda warning letter sandoz hydroxychloroquineStopping plaquenil Serious side effects have been reported with Plaquenil including the following Heart failure. Plaquenil can cause weakening of the heart muscle, resulting in heart your healthcare provider right away if you have some or all of the following symptoms of heart failure. breathlessness; swelling of the legs; irregular heart beat; fatigue; dizziness Plaquenil - Side Effects, Uses, Dosage, Overdose.. Hydroxychloroquine Plaquenil. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in some individuals.