If so, would you share a comment on the experience you have had with methotrexate; & the length of time on the medication, benefits noted, and side effects. It can be brief or as detailed as you desire to describe your experience. I used plaquenil for some time on its own, then added in MTX before changing over to leflunomide. Can yo freeze reconstituted chloroquine Antimalarial resistance chloroquine New guidelines for hydroxychloroquine guidelines 2016 pubmed Chloroquine medscape Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. WebMD explains the causes, symptoms, and treatment of Sjogren's syndrome, a condition in which your eyes, mouth, and other parts of your body get dried out. The news has been buzzing about Venus Williams dropping out of the US Open because of Sjogren's syndrome. As the media has discussed, Sjogren's is an autoimmune disease that attacks the tear and salivary glands and generally results in widespread dryness in the body. In addition to dry eyes and. I would have stayed on MTX if it worked for me, but it didn’t. I didn’t drop plaquenil until I had been on a biologic for about six months. Plaquenil and methotrexate for sjogren's syndrome Study Raises Questions about Sjogren's and Plaquenil, Sjogren's Syndrome Symptoms, Causes, Diagnosis, Treatment Chloroquine method of actionPlaquenil and nodules Have Sjogren's with symptoms of dry mouth, dry eyes use artificial tears TMJ, and constant sinus pressure/pain and sinus infections almost every three months for last 15 years had sinus surgery last year, and use Zetonna nasal aerosol and saline spray. Occasionally have acid reflux, fatigue. Sjogren's Syndrome Symptoms, Treatment & Prognosis. Why There's More to Sjogren's Syndrome The Dr. Oz Show. Methotrexate in primary Sjögren's syndrome.. Plaquenil hydroxychloroquine "I have been on this medication for approximately 8 years. Before I started this medicine I was in terrible shape. With Sjogren's syndrome as my primary autoimmune disease and rheumatoid arthritis as my secondary autoimmune disease I was in terrible persistent pain. Mar 18, 2012 Plaquenil won't directly affect dry-eye, but it can slow the progress of the disease and, therefore, hopefully slow down the rate at which your body is attacking your tear glands in other words, it might not make things better, but it may keep them from getting worse. Plaquenil has been a lifesaver for me in so many ways. Methotrexate and Sjogren syndrome - from FDA reports Summary Sjogren syndrome is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Dizziness.