Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine dangers Plaquenil exfoliative dermatitis Arava and plaquenil Chloroquine for the treatment of Viral infections Chloroquine was also studied in patients who got infected with the Chikungunya virus. The drug was effective in the non-human primate model but it enhanced chikungunya virus replication and delayed cellular and humoral responses. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. Common side effects include muscle problems, loss of appetite, diarrhea, and skin rash. Serious side effects include problems with vision, muscle damage, seizures, and low blood cell levels. It appears to be safe for use during pregnancy. Chloroquine is a member of the drug class 4-aminoquinoline. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Dosage of chloroquine in chikungunya Paradoxical Effect of Chloroquine Treatment in Enhancing., Chloroquine Oral Route Proper Use - Mayo Clinic Mechanism plaquenilHydroxychloroquine porphyria cutanea tarda moa In their Review on chikungunya, Gilles Pialoux and colleagues1 quote a Reflection and Reaction commentary previously published by our group2 as the source for the statement that “a clinical trial in South Africa failed to confirm the clinical efficacy of chloroquine on arthralgia”. It is true that chloroquine displays antiviral and anti-inflammatory properties that, in our opinion, merit. On the use of chloroquine for chikungunya - The Lancet.. Chloroquine - Wikipedia. Aralen, Chloroquine phosphate chloroquine dosing.. Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided. On the use of chloroquine for Chikungunya. Article PDF Available. to our previous studies, in that the chloroquine dosage. adopted ie, 250 mg daily 11 is inconsistent with the tissue. Dose Optimization of Chloroquine by Pharmacokinetic Modeling During Pregnancy for the Treatment of Zika Virus Infection. chikungunya and Zika virus infections–an.