Part of that is due to less exercise, part due to having no appetite thus feeling like anything I can get down is ok. Well, now I've been exercising at almost my pre-Lupus rate (ran a marathon a year before), eating a more moderate diet (clean protein, vegs & fruits), and am no longer taking that weight & bloat causing Prednisone (off Pred almost 2 yrs now). My question: Do you feel like you've gained weight on Plaquenil (ie without Prednisone)? Plaquenil cause blindness Plaquenil side effects liver Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications. My Lupus has been really quiet for about 2 yrs, and I'm afraid to change anything. The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. My rheumy wants me to come down and then off my Plaquenil, but I've been resisting simply because I'm afraid to. Hydroxychloroquine side effects weight gain Hydroxychloroquine Side-effects, uses, time to work, Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Chloroquine retroviral transfectionChloroquine how does it work Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. Hydroxychloroquine Oral Route Precautions - Mayo Clinic. Protecting your eyesight when taking Plaquenil Lupus.. Weight gain while on Plaquenil? lupus. My question Do you feel like you've gained weight on Plaquenil ie without Prednisone? The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. What's happened with you? My rheumy wants me to come down and then off my Plaquenil, but I've been resisting simply because I'm afraid to. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Hi everyone. I know this seems shallow and there are more important things in life like getting healthy but I have a question for those who are taking or have taken Medrol and or Plaquenil. Has anyone experienced weight gain? I have been reading up on side effects and weight gain and swollen face.