One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Antiboptics and plaquenil Plaquenil grapefruit How does hydroxychloroquine work in ra Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Abstract Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Safe dosing by general practitioners and hospital specialists is likely to reduce the incidence of hydroxychloroquine retinopathy in patients at risk 7. A useful aide memoir for these guidelines for hydroxychloroquine is the 5 × 5 rule ideally keep dosage 5 mg/kg/day and screen after five years of drug use. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Downes sm hydroxychloroquine retinopathy Hydroxychloroquine - Wikipedia, Recommendations on Screening for Chloroquine and. What drug class is hydroxychloroquineWhat happens if i overdose on celecoxib and plaquenilHydroxychloroquine natural alternativesAffect of hydroxychloroquineHydroxychloroquine prices canada We agreed with the conclusions of Latasiewicz et al 1 ‘Hydroxychloroquine retinopathy an emerging problem’, which cited cases of hydroxychloroquine HCQ-induced retinal damage. Three patients had received 400 mg HCQ daily for over 15 years equaling 4.93 mg/kg/day in two and 5.6 mg/kg/day in one and all developed maculopathies of varying severity. Hydroxychloroquine and the eye an old unsolved problem. The Royal College of Ophthalmologists recommendations on.. Hydroxychloroquine retinopathy Eye. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Heumatologists use hydroxy- chloroquine sulfate Plaquenil, Concordia Pharmaceuticals to treat autoimmune diseases, namely discoid or systemic lupus erythematosus, rheumatoid arthritis, Sjögren syndrome, and malaria. When taken at high doses and for long dura- tions, hydroxychloroquine has been known to cause parafoveal retinal toxicity. Hydroxychloroquine retinal toxicity is far more common than previously considered; an overall prevalence of 7.5% was identified in patients taking HCQ for greater than 5 years, rising to almost 20% after 20 years of treatment. This review aims to provide an update on HCQ/CQ retinopathy.