It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Plaquenil ophthalmic side effects Drug metabolism of plaquenil Dayquil drug interactions hydroxychloroquine Sep 13, 2019 Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Side effects Hydroxychloroquine Plaquenil is one of the safest drugs in medicine. Serious side effects are rare & routine blood tests are not required. Allergy new skin rashes is unusual but it means ruling our future use. Commoner, usually mild, side effects are indigestion, ‘gurgly tummy’, diarrhoea & headache. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Rash caused by plaquenil Plaquenil – RheumInfo, Hydroxychloroquine Plaquenil Plaquenil what does it doHydroxychloroquine mechanism of action malariaHow does hydroxychloroquine kill malariaHydroxychloroquine cause peptic ulcer That type of rash is the most common side effect of plaquenil hydroxychloroquine. Plaquenil hydroxychloroquine 200mg is it causing itchy skin rash.. Plaqunil rash -. Hydroxychloroquine Side Effects, Dosage, Uses, and More. My doctor said it was photodermatitis and caused from a sensitivity to the sun caused by the plaquenil. I am having a problem with that explanation as I haven't been in the sun in a few weeks and I am still getting the rash although it isn't blistery or as bad as it was. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. I think this rash is just starting, so I don't know if it will develope into hives or what. Could this be related to the plaquenil. I have had some weird hive like rashes in the past that I was not able to get biopsied for lupus, so I don't know if this could be the case or not.