Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine plaquenil 200 mg tablet Can plaquenil cause swelling Cost hydroxychloroquine Plaquenil and Skin hyperpigmentation - from FDA reports Summary Skin hyperpigmentation is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Omniscan, and have Arteriogram. A total of 41 patients 38 women and 3 men were included in the study. The mean age was 39.2 ± 15.4 years. The hydroxychloroquine was indicated for systemic lupus erythematosus in 73.2%, dermatomyositis in 12.2%, rheumatoid arthritis in 9.8%, actinic lichen and sarcoidosis each in 2.4%. Hydroxychloroquine is converted to an inactive metabolite in the liver and excreted in urine 25% in the active form and bile. The plasma half-life is 32-50 days. Although some of the pigmentary effects are known to be dose dependent, in most cases dyschromia does not appear to be related to cumulative doses 7. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil hydroxychloroquine hyperpigmentation Hydroxychloroquine and skin darkening Hi All. - LUPUS UK, Hydroxychloroquine-induced hyperpigmentation in systemic. Chloroquine sensitivePrecaution of chloroquineHydroxychloroquine plaquenil oitcome for lupas patientsPlaquenil lyme cysts Sep 13, 2019 Applies to hydroxychloroquine oral tablet Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Plaquenil Side Effects Common, Severe, Long Term -. Persistent cutaneous hyperpigmentation due to.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine-Induced Hyperpigmentation. From the Departments of *Rheumatology and †Dermatology, Walter Reed National Military Medical Center; and ‡Uniformed Services University of the Health Sciences, Bethesda, MD. No financial support was received for this study. The authors declare no conflict of interest. Sep 13, 2019 Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Annular atrophic lichen planus AALP is a rare variant of lichen planus. The clinical presentation of AALP shows distinct atrophic plaques with elevated borders on the trunk and extremities. Histopathologic findings generally reveal a lichenoid dermatitis in active lesions with a distinct loss of elastic fibers in the center of the lesions.