Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine vs doxycycline Sjogrens and plaquenil NSAIDs are used to treat pain, inflammation, and stiffness due to lupus. These medications are available as over-the-counter OTC and prescription drugs. hydroxychloroquine Plaquenil. NSAIDs are milder than many other lupus drugs and may be taken either alone to treat a mild flare or in combination with other medications. Skip to primary navigation Skip to main content Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil and nsaids Plaquenil and NSAIDS - Spondylitis Association of America., Treating Lupus with NSAIDs Johns Hopkins Lupus Center Taking chloroquine in pregnancyLeflunomide hydroxychloroquine combinationPlaquenil diarrhea nausea The treatment of psoriatic arthritis is usually started with NSAIDS ibuprofen being one. While hydroxychloroquine Plaquenil can be used, it is usually avoided in that condition because of the risk of a condition known as 'exfoliative dermatitis' or even worsening the psoriatic arthritis itself. Is it ok to take ibuprofin and hydroxychloroquine sulfate.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Drug interactions are reported among people who take Plaquenil and Ibuprofen together. This study is created by eHealthMe based on reports of 1,051 people who take Plaquenil and Ibuprofen from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 15 million FDA reports. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis.