It will look at – in detail – quinine and quinine-related drugs. In a previous article, we briefly described malaria and artemisinin as a lead compound for new antimalarials. Basic description of chloroquine Can you take plaquenil with benadryl Can hydroxychloroquine affect graves disease Chloroquine er derived vaculation Feb 07, 2009 It's functional groups are * alkene * tertiary amine the quinuclidine bicyclic system * secondary alcohol * quinoline an aromatic system, specifically 1-azanaphthalene * phenolic ether or perhaps simply an aromatic ether A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Chloroquine is an aminoquinoline that is quinoline which is substituted at position 4 by a 5-diethylaminopentan-2-ylamino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis. Understanding the chemistry of these compounds also, as it happens, makes it much easier to comprehend the pharmacology and therapeutic management of malaria itself. We now turn our attention to the other antimalarial drugs. Chloroquin functional groups CHLOROQUINE Drug BNF content published by NICE, Chloroquine Indications, Side Effects, Warnings - Plaquenil cause insomniaPlaquenil and mixed connective tissue diseaseHow long does plaquenil take to kick in Phenacetin has functional parent 4-ethoxyaniline CHEBI85505 phenacetin has functional parent N-phenylacetamide CHEBI28884 phenacetin has functional parent paracetamol CHEBI46195 phenacetin has role cyclooxygenase 3 inhibitor CHEBI73263 phenacetin has role non-narcotic analgesic CHEBI35481 phenacetin has role peripheral nervous system drug CHEBI49110 phenacetin is a acetamides CHEBI22160 phenacetin is a aromatic ether CHEBI35618 Phenacetin CHEBI8050. Chloroquine C18H26ClN3 - PubChem. Chloroquine Side Effects Common, Severe, Long Term -. Chloroquine was one of the drugs successfully developed. The drug was first used during the 1950s. Chloroquine is effective against erythrocytic forms of the Plasmodium parasite. Like chloroquine, the drugs amodiaquine and hydroxychloroquine belong to a class of quinine analogues called 4-aminoquinolines. The dosage for adults may also be calculated on the basis of body weight; this method is preferred for infants and children. A total dose representing 25 mg of base per kg of body weight is administered in three days, as follows First dose 10 mg base per kg but not exceeding a single dose of 620 mg base. Common Functional Groups. Some functional groups contain just a single atom, such as the chloro group shown above. Others are made up of two or more atoms working together as a unit as with the lactam and the imine. A large number of functional groups including lactams contain the carbonyl group C O.