It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Plaquenil addictive Chloroquine method of action Plaquenil and Rashes - from FDA reports Summary Rashes is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Pain. If you definitely cannot take the plaquenil, then you should speak with your rheumy about starting may make you start to feel better. There are other anti-malaria drugs on the market that your rheumy can put you on instead of the plaquenil. But, make sure the he/she is convinced that you are actually allergic to the plaquenil. How is plaquenil hydroxychloroquine used to treat lupus? ANSWER Plaquenil hydroxychloroquine is commonly used to help keep mild lupus-related problems, such as skin and joint disease, under. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. How to treat plaquenil rash Addressing DRESS A Case of a Hydroxychloroquine-Induced., Allergic reaction to plaquenil DailyStrength Is plaquenil still the go drug for lupud Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. How is plaquenil hydroxychloroquine used to treat lupus?. Lupus Skin Rash Treatments That Actually Work - Blog. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Plaquenil has beneficial effects on 3 major aspects of lupus; skin rashes, aches & pains and fatigue. It has also been found to help in a number of other features of the disease, though less predictably. It is very effective in the treatment of a whole variety of lupus skin rashes, particularly those found to be worsened by sunlight. Potential side effects of anti-malarial drugs include Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish tone. Dry skin. Loss of appetite. Abdominal bloating. Upset stomach.