Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Effect of plaquenil on eyes Weight loss from plaquenil Plaquenil contraindications ativan Hydroxychloroquine sulphate uses Abnormal weight gain is a side effect of long-term doxycycline and hydroxychloroquine treatment. Gut microbiota modifications at the phylum level could play an instrumental role in this effect. We highlight the need for specific nutritional care in patients undergoing long-term antibiotic treatment, particularly treatment involving the use of. I've had lupus for over twenty years and only in the last two years have I had a problem with weight loss, no appetite. I've lost over twenty pounds in the last two years and am struggling to gain any weight back. I'm 5' 7" tall and I weigh about 115 lbs. I should weigh around 130 lbs. I've recently gained five pounds back, woohoo! Re want to know good stuff about plaquenil Hi Aspen.answer to your question, I have been diagnosed PlaquenilName brand-Not the generic form twice in my life, about 15 yrs ago for Sjogren's Syndrome-for about a year & then again last year when I was diagnosed with Lupus. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil weight gain lupus Plaquenil and loss of appetite - Lupus - MedHelp, Lupus and weight loss - Lupus - Inspire Chloroquine or prophylaxisLysosomal inhibitor chloroquine Health related message boards offering discussions of numerous health topics including allergies, cancer, diabetes, heart disease, exercise, attention deficit disorder, diet, and nutrition. Lupus Board Index plaquenil weight gain - Page 2 Lupus Board Index plaquenil weight gain - Page 2. Want to know good stuff about plaquenil - HealthBoards. Protecting your eyesight when taking Plaquenil Lupus.. The symptoms of lupus vary wildly—from unexplained weight loss to rashes. As a result, it's rare for patients to show up at the doctor's office with symptoms that clearly point to the disease. Aug 01, 2009 My weight gain is from the steroids I'm certain and not the Plaquenil. Are you on anything else to treat your lupus other than the Plaquenil? If you're on steroids that can be whats causing you to gain weight. I can't offer any advice on losing the weight if you come off the Plaquenil. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as.