If so, how long does it take to make pain and stiffness go away? My dr is using it trying to get rid of all of my joint pain and stiffness that seems to be taking over my body. I had a pretty bad flare right after Christmas and my rheumy added methotrexate to what I was already taking. I don't know for sure if it is the plaquenil or other meds but my rheumy seems to have my inflammation/stiffness under pretty good control. Just rediced plaquenil from one tablet twice a day to one tablet once a day. I have noticed an improvement but it's very little. Chloroquine phosphate injection Chloroquine side effect homicide Not diagnosed with rd but on methotrexate and plaquenil Summary Muscle aches is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration. Track DMARD Effects. DMARDs are often standard treatment for rheumatoid arthritis. Even if you've been taking them a while, you still need to track how well they work and watch for side effects. Home remedies for joint pain and stiffness include taking a warm shower or bath, or applying a heating pad or ice pack. Apply ice if your joint is inflamed. Rest can also relieve these two common lupus symptoms. Avoid putting weight on the affected joint, or performing any activity that stresses it, and support it with a pillow or cushion. He encouraged me to stay with it 3-4 months in order to get the full effect of any help I may receive. However, I think I may be getting migraines from it?! Just remember everyone has a different reaction to the various meds. I don't know if the plaq or MTX or prednisone is what's helping. Plaquenil takes quite a long time to get to its peak effectiveness: depending on what you read, anywhere from 3 months to a year. I also take Cimzia injections bi-weekly but that has only been for about 6 months. Although I do have to give credit to my rheumy because after just a month or two I wanted to be taken off the Cimzia as I didn't think it was really doing much. Hi brandi, I tried Plaquenil, unfortunately for me the side effects is what took me off of it. The kind where I wanted to scratch every inch of my skin off. Took about a week of taking 2 kinds of allergy meds before I got rid of that effect. I have 2 days a week, after my MTX, where I'm just sick. I've been on the MTX now for about a month and when I see my rheumy in 2 weeks I'm going to see if I can try something else or stop taking it. Plaquenil and muscle stiffness PLAQUENIL Side Effects, Reviews by Patients -, Track DMARD Effects - WebMD Cual es la pastilla aralenHydroxychloroquine side effects testWhat drug class is hydroxychloroquine About 23 years later, she was diagnosed with lupus and started treatment with Plaquenil hydroxychloroquine to manage joint swelling and tenderness. During this period, her MG symptoms got worse, with eyelid weakness and facial asymmetry with muscle paralysis. In MG/Lupus Overlap, Thymus May Play Key Role, Case Series.. Coping with Common Lupus Symptoms and Treatments. Experiences taking Plaquenil for Fatigue and Muscle Pain.. Muscle weakness also may be a side effect of certain drugs used to treat lupus and related conditions, including prednisone and other corticosteroids, cholesterol-lowering drugs and hydroxychloroquine Plaquenil®. Therefore, drug-induced muscle disease should be ruled out as a cause of weakness if you are taking any of these medications, as drug-induced muscle weakness usually does not produce elevated levels of muscle enzymes as is seen in lupus myositis. Hydroxychloroquine Plaquenil is commonly used for treating joint pain in Sjögren’s syndrome patients, based in part on its efficacy in treating the joint pain of patients with systemic lupus erythematosus and rheumatoid arthritis. I've been on it a year, reluctantly. I do not want to have to be maintained on any chemicals or pills. Now that I've been on it a year the only thing that has improved is fatigue. But I"m not sure if it's because the flare passed or because of plaquenil. I still get joint, muscle and back pain so to me it hasn't improved the pain part of it.