It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Chloroquine sold where Plaquenil optic neuropathy Chloroquine for restless leg syndrome Hydroxychloroquine pill Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. Major Depression is #139 concern in Plaquenil discussions. Plaquenil is an arthritis medication and an anti infectious agent. Uses Plaquenil is prescribed for Lupus, RA, Sjogren's Syndrome and Joint Pain and is mostly mentioned together with these indications. Jan 12, 2014 Swinging hypothyroid can cause mood swings, depression and constipation. I took Plaquenil for six years and am really not sure whether I suffered any side effects or not. I think it may have contributed to tinnitus and I came off i9t in case it was contributing to balance issues. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Can plaquenil cause depression Is extreme fatigue a side effect of Plaquenil?, Can Plaquenil cause Major Depression? - Treato Chloroquine and hearing lossHow long for plaquenil rash to go awaySide effectsof chloroquineChloroquine retinopathyHydroxychloroquine rash Find information about common, infrequent and rare side effects of Plaquenil Oral. Common and Rare Side Effects for Plaquenil Oral. Plaquenil causing mood changes and depression?. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Plaquenil and Stress and anxiety - from FDA reports Summary Stress and anxiety is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Pain.