If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range (/= 6.5 mg/kg/day). This graph shows various formulas that have been proposed for deriving ideal body weight for women, because virtually all cases of hydroxychloroquine toxicity have been female. Can you take hydroxychloroquin and eliquis How does hydroxychloroquine work for lupus Hydroxychloroquine brands Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Dosage is based on body weight. The typical. Discussion. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a patient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity. Adults— Standard dosing At first, 800 milligrams mg 4 tablets taken as a single dose. Then, 400 mg taken 6 hours, 24 hours, and 48 hours after the first dose. Weight-based dosing Dose is based on body weight and must be determined by your doctor. At first, 13 milligram mg per kilogram. For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. The usual hydroxychloroquine dose that is prescribed is 400 mg/day. Weight based dosing plaquenil Plaquenil hydroxychloroquine sulfate dose, indications., Plaquenil Risk Calculators Cyp2d6 and plaquenil Background/Purpose Hydroxychloroquine HCQ is a widely-used medication in many rheumatologic conditions. The most worrisome toxicity is irreversible damage to retinal pigment epithelium which can lead to blindness. The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity1. According to these New Guidelines on Hydroxychloroquine Dosage - Where Are We.. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Adherence to Weight-Based Dosing Guidelines in Patients.. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Dec 30, 2015 SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day. The study is based on hydroxychloroquine sulfate the active ingredients of Plaquenil and Plaquenil the brand name. Other drugs that have the same active ingredients e.g. generic drugs are not considered. Dosage of drugs is not considered in the study.