Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Easily bruising side effect of plaquenil Plaquenil and heartburn Patients who get a drug exanthem with hydroxychloroquine may be able to tolerate chloroquine, while an urticarial reaction from hydroxychloroquine would preclude use of chloroquine. Other side effects include nausea, headaches, myopathy, and bluish-gray hyperpigmentation of the skin. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Lichen planus pigmentosus LPP is a rare form of lichen is characterized by oval or irregularly-shaped brown to gray-brown macules and patches on the skin. Areas that are exposed to sun such as the forehead, temples and neck are most commonly affe Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil hyperpigmentation Common and Rare Side Effects for Plaquenil Oral, Plaquenil Side Effects Common, Severe, Long Term - Hydroxychloroquine antiviralOtis pregnancy plaquenilPlaquenil solar urticariaHydroxychloroquine makes me feel worseOcular effects of hydroxychloroquine Free, official coding info for 2020 ICD-10-CM T37.8X5A - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more. ICD-10-CM Diagnosis Code T37.8X5A Adverse effect of.. Lichen planus pigmentosus Genetic and Rare Diseases.. Systemic Scleroderma Skin Involvement Hyperpigmentation and.. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. However, following an identical dose of. Hydroxychloroquine is an antimalarial medication that can cause hyperpigmentation of nails, mucosa, and skin 1–5. Retrospective studies cite the incidence of drug-related hyperpigmentation from hydroxychloroquine to be as high as 33% of individuals. Elder abuse is a cause of significant morbidity and mortality in older individuals 7–9. I think it's due to Hydroxycholoroquine-induced hyperpigmentation an example of drug-induced skin pigmentation. I thought it worth showing those of you on the medication. Why is it so much worse on the right forearm? Well she's only just started to drive again.