Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil a steroid Scarring alopecia plaquenil dosage Plaquenil discontinuation syndrome Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. This medication may make these conditions worse. Call 911 if your symptoms feel life-threatening. Hi everyone, I am wondering if anyone has had a problem with fatigue while on Plaquenil. I have been on it for about. 3 months now. At first, I was nauseous for a week or so, which the dr. told me could be a side effect. After the nausea went away it seemed like my pain got worse for a week or so, and then it gradually got better. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine makes me feel worse Hydroxychloroquine and tinnitus Does anyone think, or. - NRAS, Is extreme fatigue a side effect of Plaquenil? Side effects of chloroquine overdoseExpired chloroquineHydroxychloroquine mechanism of action lupusPlaquenil and light sensitivity Does anyone else feel worse on Plaquenil? Support Forums Rheumatoid Arthritis New Topic Reply. Made me feel out of it all the time, sort of dizzy and ou of balance. I had to go off it after 6 weeks. They put me on methotrexate and that worked much better. Goodluck, golitho Does anyone else feel worse on Plaquenil?. Hydroxychloroquine Plaquenil -. Rheumatoid Arthritis and Sleep Arthritis Foundation. Hydroxychloroquine received an overall rating of 7 out of 10 stars from 368 reviews. See what others have said about Hydroxychloroquine, including the effectiveness, ease of use and side effects. User Reviews for Hydroxychloroquine. Also known as Plaquenil, Quineprox The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. On plaquenil always made me feel very bad. hate it. before my diagnosis I was tired,aneamic,stiff etc since the plaquenil I jus flare all the time. it was so bad I just came off it for several months. got so ill they wanted me to go on chemo based drugs but I did not want that either. so reluctantly went back on the plaquenil. imo its made me worse.