May also be prescribed off label for Sjogren's Syndrome, Undifferentiated Connective Tissue Disease. " Prescribed for Lyme Disease - Arthritis, Dermatomyositis, Malaria, Malaria Prevention, Rheumatoid Arthritis, Systemic Lupus Erythematosus. Chloroquine phosphate Effects of plaquenil on the eyes Using multivariate logistic regression, we found that HCQ-induced pigmentation was independently associated with previous treatment with oral anticoagulants and/or antiplatelet agents and with higher blood HCQ concentration. Conclusions and Relevance Hydroxychloroquine-induced pigmentation is not a rare adverse effect of HCQ. Our data support the hypothesis that HCQ-induced pigmentation is secondary to ecchymosis or bruising. Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. Jan 01, 2020 Drugs that prolong QT interval and other arrhythmogenic drugs Plaquenil prolongs the QT interval and should not be administered with other drugs that have the potential to induce cardiac arrhythmias. Also, there may be an increased risk of inducing ventricular arrhythmias if Plaquenil is used concomitantly with other arrhythmogenic drugs. Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. Side effects can be severe and potentially fatal so a full assessment of the risks versus benefits is required before methotrexate is prescribed. May also be prescribed off label for Sjogren's Syndrome,... Plaquenil and antiplatelet drugs PLAQUENIL hydroxychloroquine sulfate Label, Drugs & Medications - WebMD Chloroquine and primaquine treatment The platelet is integral to the initiation of thrombosis. 1 Drugs that affect platelet function are a fundamental part of primary and secondary management of atherosclerotic thrombotic disease. 2 As reviewed in various guideline documents, 3 authoritative reviews, and meta-analyses, the indications for the use of antiplatelet drugs in the. Antiplatelet Drugs A Review of Their Pharmacology and.. Plaquenil - FDA prescribing information, side effects and uses. Plaquenil Disease Interactions -. Antiplatelet drugs have haemorrhage as a common side-effect. Several factors associated with a higher risk of bleeding have been identified, including female sex, advanced aged 75 yr, impaired renal function, anaemia, low body weight 60 kg, and a history of transient ischaemic attack or stroke. BACKGROUND With the inflammatory model of atherosclerosis taking center stage, anti-inflammatory drugs hold a promising place in the therapy of cardiovascular disease CVD. Recent studies showed that hydroxychloroquine HCQ was protective against thrombovascular events in lupus erythematosus and traditional cardiovascular risk factors in patients with rheumatoid arthritis. Drugs That Prolong QT Interval And Other Arrhythmogenic Drugs. PLAQUENIL prolongs the QT interval and should not be administered with other drugs that have the potential to induce cardiac arrhythmias. Also, there may be an increased risk of inducing ventricular arrhythmias if PLAQUENIL is used concomitantly with other arrhythmogenic drugs.