Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine kidney disorders problems Ara patient information hydroxychloroquine Is plaquenil safer than methotrexate Plaquenil retinal damage Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash. Kidney stones is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Osteoporosis. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil kidney side effects Will you have Acute kidney failure with Plaquenil - eHealthMe, Will you have Kidney stones with Plaquenil - eHealthMe How to tell if plaquenil is causing blindness People reported to have side effects when taking Plaquenil. Among them, 13 people 0.02% have Renal function test abnormal Will you have Renal function test abnormal with Plaquenil.. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Plaquenil side effects Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye.