Although it is uncommon, lupus can also attack a patient’s liver, causing a more pronounced elevation in liver enzymes, such as ASTs and ALTs. When this happened to me, my symptoms included pervasive malaise, nausea, itching, and worsening of my overall health and lupus activity. Chloroquine phosphate 250 mg base Plaquenil 200 mg qd Plaquenil maculopathy cumulative dose Hydroxychloroquine for alopecia areata Elevated liver enzymes often indicate inflammation or damage to cells in the liver. Inflamed or injured liver cells leak higher than normal amounts of certain chemicals, including liver enzymes, into the bloodstream, elevating liver enzymes on blood tests. The elevated liver enzymes most commonly found are I don't think so. From what I read, it is likely because CQ and HCQ increase endosomal pH, which disrupts action of several enzymes required for viral replication. This action presumedly also inhibits the production of some inflammatory enzymes, thus why it is effective in some autoimmune disorders. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. They consulted and referred me to a gastroenterologist. My family doctor was persistent in finding an answer, and wouldn’t let my rheumatologist rest until they found one. Plaquenil increase liver enzymes Will you have Liver function test abnormal with Plaquenil., Hydroxychloroquine Plaquenil thread COVID19 Chloroquine and alcohol consumption A low-dose chemotherapy drug; hydroxychloroquine; an anti-malaria drug; drugs like Enbrel; which are known as tumor-necrosis factor; or TNF; inhibitors; All of these medications can cause damage to the liver and increased liver enzymes. Let your physician know before starting these medications if you have any history of liver disease. Rheumatoid Arthritis & Elevated Liver Enzymes Healthfully. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Top Causes of Elevated Liver Enzymes + How to Treat High AST.. An increase in cholesterol and liver enzymes is also a risk. Corticosteroids. Corticosteroid drugs help fight inflammation and depress your immune response. Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. There is no Elevated liver enzymes reported by people who take Plaquenil yet. This review analyzes which people have Elevated liver enzymes with Plaquenil. It is created by eHealthMe based on reports from Food and Drug Administration FDA, and is updated regularly.