Controlled studies in pregnant women show no evidence of fetal risk. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. Animal studies show risk and human studies not available or neither animal nor human studies done. Contact the applicable plan provider for the most current information. D: Use in LIFE-THREATENING emergencies when no safer drug available. Plaquenil immunoglobulin receptor Plaquenil helped my fatigue The Weight Based Dose Calculator is used for weight based dosing. The parameters for the calculator include dosage, weight, med amount, per volume. This represents a total dose of 2.5 g chloroquine phosphate or 1.5 g base in three days. The dosage for adults of low body weight and for infants and children should be determined as follows First dose 10 mg base per kg but not exceeding a single dose of 600 mg base. Recommended prophylactic dose is about 5 mg/kg maximum 250 mg/dose orally once a week. -This drug should be taken on the same day of each week, preferably after the main meal. -Prophylaxis should begin 1 week before arrival in an endemic area, continue during the stay, and then continue for 4 weeks after leaving the area. Active against erythrocytic forms of Plasmodium vivax & P. malariae and most strains of Plasmodium falciparum Precise mechanism not known Bioavailability: ~89% Peak plasma time: 1-2 hr Distributed widely in body tissues (eg, eyes, heart, kidneys, liver, lungs) where retention prolonged; crosses placenta; enters breast milk Partially in liver Half-life: 3-5 days Excretion: urine (~70% as unchanged drug); acidification of urine increases elimination Small amounts may be present in urine months following discontinuation of therapy The above information is provided for general informational and educational purposes only. Chloroquine dose per kg Chloroquine - FDA prescribing information, side effects and uses, Aralen Chloroquine Uses, Dosage, Side Effects. Plaquenil toxicity in macular octVisual field plaquenil Quinine sulfate, quinine hydrochloride, and quinine dihydrochloride come in tablets of 300 mg and their dose is the same. By body weight, the dose is 10 mg of quinine sulfate per kg taken 3 times a day. Quinine bisulfate tablets, however, have a different dose 14 mg per kg taken 3 times a day. More Medicines Used for Malaria - Hesperian Health Guides. Mefloquine Dosage Guide with Precautions -. Chloroquine Prevention of Coronavirus Disease COVID-19 in.. This represents a total dose of 2.5 g Chloroquine phosphate or 1.5 g base in three days. Infants and Children In infants and children, the recommended dose is 10 mg base/kg followed by 5 mg based/kg at 6, 24 and 36 hours total dose 25 mg based/kg. The pediatric dose should never exceed the adult dose regardless of weight. A metabolite of chloroquine – hydroxychloroquine – has a long half-life 32–56 days in blood and a large volume of distribution 580–815 L/kg. The therapeutic, toxic and lethal ranges are usually considered to be 0.03 to 15 mg/l, 3.0 to 26 mg/l and 20 to 104 mg/l, respectively. Jun 08, 2009 In this study, a dose of 15 mg/kg chloroquine was given to the mother mice, because this dose resulted in nearly 100% survival of the pups. For the setup of this test, pregnant mice were divided into three groups. Only the mother mice from group 1 were treated with chloroquine 1 day prepartum.