Derm Net NZ Medical Editor: Dr Delwyn Dyall-Smith, Dermatologist, Wagga Wagga, NSW, Australia. However, following an identical dose of hydroxychloroquine and chloroquine, tissue levels of chloroquine are 2.5 times those of hydroxychloroquine. Derm Net NZ Editor in Chief: Adjunct Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand. Hydroxychloroquine is preferred due to its safer profile. Does plaquenil have withdrawal symptoms Hydroxychloroquine retinal toxicity Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells anemia. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell. Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation. If there is a of hydroxychloroquine, although studies have not usually confirmed this clinical impression. Plaquenil face rash Plaquenil and itching -, Hydroxychloroquine Plaquenil Side Effects & Dosage for. Chloroquine drug cardPlaquenil teethHydroxychloroquine gastrointestinal side effects The typical dose for hydroxychloroquine is 200-400mg per day and is based on a person’s body weight or if you are overweight, your ideal body weight. While hydroxychloroquine is considered a relatively safe medication, like all medications there are potential risks. These include body rashes that often will itch. Ask the Expert Plaquenil and Sjögren’s. Common and Rare Side Effects for Plaquenil Oral. Lupus Skin Rash Treatments That Actually Work - Blog. Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. Rashes is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Pain PLEASE HELP! I have been on Plaquenil well the generic form-- hydroxychloroquine since October, and for the past about 2 weeks, I have been SEVERELY skin turns red, and it feels like something is biting me. It's bad around my ankles and the tops of my feet, my arms, and I get red blotches and spots on my chest.