I didn't seem to have any problems whatsoever with it initially, other than very short term and mild cramping/diarrhea. But now I've been dealing with considerable muscle aching and pain/spasm in some new places - or at least places that haven't bothered me in quite awhile. Plaquenil and bone loss Plaquenil canadian drug plan Order aralen prescribing Knee pain was the most common complaint, followed by shoulder and hip pain, but joint pain can affect any part of your body, from your ankles and feet to your shoulders and hands. As you get older. Lupus arthritis causes pain, stiffness, swelling, tenderness and warmth in your joints. The joints most often affected are the ones farthest from the middle of the body, such as fingers, wrists, elbows, knees, ankles and toes. It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works. How to use Plaquenil Hydroxychloroquine is usually taken with food. I felt the Plaquenil helped the fatigue, but it seems the pain is sabotaging that effect. My knees and legs hurt, back, hips, shoulders, fingers, and now my left heel - which has me limping half the time. Can plaquenil cause joint pain Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis., How Lupus Affects the Muscles, Tendons and Joints Lupus. Plaquenil and citalopram qt prolongationCalcium chloroquine fc reviewReview of optometry plaquenil guidelines Plaquenil and Joint pain - from FDA reports Summary Joint pain is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain. Will you have Joint pain with Plaquenil - eHealthMe. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil causes and treats neuropathy? - NeuroTalk Support.. Tell your doctor if you experience serious side effects of Plaquenil including. muscle weakness, twitching, uncontrolled movement, loss of balance or coordination, blurred vision, light sensitivity, seeing halos around lights, Hate it. before my diagnosis I was tired,aneamic,stiff etc since the plaquenil I jus flare all the time. it was so bad I just came off it for several months. got so ill they wanted me to go on chemo based drugs but I did not want that either. so reluctantly went back on the plaquenil. imo its made me worse. I've been on plaquenil for 6 months now and I still have significant joint pain! I can't say that the drug has helped at all, but it is difficult to compare todays pain with that of 6 months ago. I still get extremely tired for days on end. Still get mysterious rashes, fevers and other odd symptoms.