Additionally, another exception occurred while executing the custom error page for the first exception. The new guideline on screening for hydroxychloroquine and chloroquine retinopathy is written in response to evidence from the United States that shows that hydroxychloroquine retinopathy is more common than previously recognised. Effects of plaquenil on the eyes Pregnancy hydroxychloroquine Adequately monitored and to act on the results of monitoring. A useful aide memoir for these guidelines for hydroxychloroquine is the 5 x 5 rule ideally keep dosage 5mg/kg/day and monitor after five years of drug use. Hydroxychloroquine and Chloroquine Retinopathy Recommendations on Monitoring Clinical Guidelines Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ. My Take on New Ocular Screening Guidelines for Plaquenil By Sergio Schwartzman, MD 12 October 2016 A recent article published by the American Academy of Ophthalmology AAO presented new recommendations for screening of patients being managed with hydroxychloroquine HCQ. The new guideline also makes recommendations regarding the techniques and timing of baseline and follow-up screening tests for both hydroxychloroquine and chloroquine retinopathy. Implementation of the guideline’s recommendations will prevent iatrogenic visual loss. Chloroquine maculopathy guideline Revised recommendations on screening for chloroquine and., Chloroquine and Hydroxychloroquine Toxicity Guidelines. Plaquenil toxicity screening recommendationsPlaquenil dark skinIs chloroquine available over the counterMode of action of chloroquinePlaquenil for dermatomyositis Plaquenil hydroxychloroquine sulfate, Sanofi-Aventis and the less-used chloroquine are antimalarial drugs with anti-inflammatory properties that are used for the management of a spectrum of inflammatory conditions. How to Succeed in Plaquenil Screenings. My Take on New Ocular Screening Guidelines for Plaquenil RheumNow.. HYDROXYCHLOROQUINE Shared Care Guideline V1. The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. It succinctly makes the case for screening, and Contraindications include pre-existing maculopathy of the eye. Caution is advised in patients with renal or hepatic disease, with sensitivity to quinine, those with glucose-6-phosphate dehydrogenase deficiency, those with porphyria cutanea tarda which can be exacerbated by hydroxychloroquine and Most cases of chloroquine retinopathy have developed when a higher than currently recommended 3 mg/kg/day using lean body weight dose was used. 21 A daily dose exceeding 250 mg with a total cumulative dose between 100 and 300 g is customarily needed to produce toxicity. 22 One study showed a 19% incidence of chloroquine retinopathy in patients taking a mean daily dose of 329 mg. 23 On the other hand, with strict adherence to a low dose per day, the incidence of retinal abnormalities is.