But there's evidence the drug can activate a virus that can increase the risk of lymphoma and similar cancers in some patients. A number of reports have linked methotrexate with lymphoma and similar cancers of the lymph glands, says senior researcher Shannon C. Kenney, MD, a microbiologist and infectious disease specialist with the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill. Plaquenil calculator Plaquenil alcohol liver Hydroxychloroquine package insert Malaria chloroquine prophylaxis Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 What Conditions Does This Treat? Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Some studies have indicated that the drug's immune-weakening effect places people at risk for viral-associated lymphomas. Also, studies have shown that when rheumatoid arthritis patients quit taking methotrexate, their lymphoma went into regression, another sign that the drug directly contributes to the cancer, she tells Web MD. Hydroxychloroquine increse methotrexate Does anyone take methotrexate and hydroxychloroquine., RA and Hydroxychloroquine How Effective is it for Rheumatoid. Plaquenil and ivfHydroxychloroquine 25mg Administration of hydroxychloroquine with penicillamine Cuprimine, Depen may increase penicillamine levels, increasing the risk of penicillamine side effects. The mechanism is unknown. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Hydroxychloroquine Plaquenil. Huge price increase for methotrexate" Rheumatoid Arthritis.. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Combination therapy with methotrexate and hydroxychloroquine for rheumatoid arthritis increases exposure to methotrexate. Lower the convulsion threshold e.g. mefloquine may increase the risk of convulsions. Antiepileptics The activity of antiepileptic drugs might be impaired if co-administered with PLAQUENIL. Methotrexate Combined use of methotrexate with PLAQUENIL has not been studied and may increase the incidence of adverse effects. PLAQUENIL.