One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Anyone has uti after taking f hydroxychloroquine Can plaquenil cause nerve damage Chloroquine lung cancer MONITORING FOR PLAQUINIL-INDUCED RETINAL TOXICITY Plaquenil is used for the treatment of malaria, systemic lupus erythematosus, rheumatoid arthritis, and other inflammatory and connective tissue diseases. Retinal toxicity from Plaquenil is of serious concern because even after cessation It has become fairly common practice for most rheumatologists to recommend that patients being treated with hydroxychloroquine be seen for formal visual field evaluation once or twice a year to monitor for retinal toxicity. The previous AAO guideline recommended screening every 12 months. Currently, one of the primary functional screening tests recommended for the evaluation of Plaquenil retinal toxicity is 10-2 white stimulus automated visual fields; however, research shows Asian patients benefited from 24-2 or 30-2 visual fields, given that toxicity often manifests changes beyond the macula in these patients. 9 Because spectral-domain optical coherence tomography SD-OCT is readily accessible and able to detect early structural damage prior to clinical funduscopic findings. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil toxicity monitored 24-2 or 10-2 Hydroxychloroquine-Induced Retinal Toxicity - American., My Take on New Ocular Screening Guidelines for Plaquenil. Does plaquenil have small amounts of malaria in it Testing for Chloroquine and Hydroxychloroquine Retinopathy. Introduction Although the exact mechanism by which chloroquine CQ and hydroxychloroquine HCQ - commonly known as Plaquenil induce retinal toxicity is not well understood, but it is recognized as a serious ophthalmologic concern because it is not treatable. 1 Guidelines from the American Academy of Ophthalmology AAO on screening. This is Why You Need Multifocal ERG if You Have Plaquenil Patients. How to Succeed in Plaquenil Screenings. Plaquenil Guidelines Point Out New Risks, New Presentation.. Plaquenil Guidelines Point Out New Risks. found that real body weight was a better predictor of the risk of toxicity. 3. so you should do both 10-2 and 24-2. Plaquenil induced retinal toxicity is reversible if detected early and plaquenil dosage altered or the medication discontinued. Even suspicious early plaquenil toxicity warrants communication with the patient’s treating physician, and meaningful coordination of care would include a report even if the findings are normal. It may be given 3-4 times per week for several weeks after the intake of Plaquenil. Acidification of the urine may also improve the urinary excretion of the drug 1, 2, 3. Prevention. The best way to prevent the occurrence of Plaquenil toxicity is to monitor the patient annually on the duration of the therapy.