Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine sulfate adverse reactions When is the best time to take hydroxychloroquine Does hydroxychloroquine cause weight loss This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. My question Do you feel like you've gained weight on Plaquenil ie without Prednisone? The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. What's happened with you? My rheumy wants me to come down and then off my Plaquenil, but I've been resisting simply because I'm afraid to. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Side effects of too much plaquenil Common and Rare Side Effects for Plaquenil Oral, Plaquenil & Weight Gain/Loss - Plaquenil turns hair whitePlaquenil induced bruising on shinsPlaquenil manufacturer change side effectsChloroquine resistant vivax malaria treatmentHow do i know if i'm allergic to hydroxychloroquine Drug Information on Plaquenil, Plaquenil Sulfate, Quineprox hydroxychloroquine includes side effects, uses, drug interactions, dosage, drug pictures, overdose symptoms, and what to avoid. Plaquenil, Plaquenil Sulfate, Quineprox hydroxychloroquine Uses, Side.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hi, I've been taking Plaquenil for many years now and have never experienced any side effects or long term effects. But headache is listed as one of the "mild adverse effects". I would suggest that you try to split the dose as suggested. I've always taken 1 in the AM & 1 at night. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. If you take too much Plaquenil, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away. If you take too much Plaquenil, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.