Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine eyes treatment Plaquenil and tramadol Easy bruising or bleeding ; Frequent or severe infections ; Signs of heart problems, such as swelling of the ankles, shortness of breath, or an irregular heart rhythm arrhythmia Signs of an allergic reaction, such as An unexplained rash Plaquenil can cause severe, life-threatening rashes Hives ; Itching Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Easy bruising plaquenil Is frequent bruising a side effect of Plaquenil?, Plaquenil Uses, Dosage & Side Effects - Precautions of chloroquine Aug 14, 2017 According to the New Zealand Dermatological Society, Plaquenil can cause abnormalities in blood counts. An abnormally low number of white blood cells can lead to infection, because white blood cells defend the body against bacteria. Low platelet count thrombocytopenia can lead to easy bleeding and bruising. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Inherited disorders, such as von Willebrand disease, can affect your blood’s ability to clot and may cause easy bruising. Females bruise more easily than males. Researchers have found that each sex organizes fat and blood vessels differently within the body. The blood vessels are tightly secured in males. Easy bruising of the skin. bleeding. sensitivity to light. changes in vision. convulsions. decrease in urination. hair loss. difficulty seeing or reading. pronounced muscle weakness. mental changes or extreme mood swings. problems with hearing. View the side effects section for an in-depth look at possible hydroxychloroquine side effects. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.