I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Hydroxychloroquine schnitzler syndrome urticaria Maculopathy hydroxychloroquine Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Nov 16, 2004 Methotrexate and Lymphoma. In a series of laboratory tests involving cells with latent EBV virus, Kenney found that using methotrexate on cells that contained the latent Epstein-Barr virus activated the virus, causing an increase in the release of infectious EBV. Hi, I have been on Plaquenil an Arava for about 2 and a half years now. I was also on Orencia for 2 years. I just started back with Arthrotec. Te Orencia stopped working for me and I just started Simponi last week. I was having increased stiffness and pain in the achilles tendon area and it was real tough walking. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. Stopped plaquenil lymphoma Can Plaquenil cause Lymphoma? - Treato, Rheumatoid Arthritis Drug Linked to Cancer - WebMD Does plaquenil need to be taperedChloroquine phosphate 250 mg oral tabletPlaquenil with steroidDose of plaquenil for lupusMalaria prophylaxis with chloroquine I was put on Plaquenil for RA as I was being dx for lupus. I am very mild. My rhuemy wants me to stop every time I have an infection. When it is gone she said I can resume at my own pace. Take into consideration I only take Plaquenil and ibuprofen 800mg. My symptoms came back after two weeks of being off it. Stopping Plaquenil - General Discussion - Life With Lupus. PLAQUENIL" Rheumatoid Arthritis Community - Support Group. Perioperative Management of Medications Used in the Treatment.. It is generally recommended that these agents be discontinued in patients with a recent diagnosis of cancer, so most patients will have stopped biologics before surgery. Case 2 A 44-year-old woman with seropositive rheumatoid arthritis, on triple-DMARD therapy methotrexate, sulfasalazine, and hydroxychloroquine, presents with a 1.5-cm nodule. If you don't have to, don't stop your plaquenil. I stopped taking the plaquenil the beginning of December. It doesn't agree with my stomach I take it with meals too. And since I hadn't had a miraculous recovery the 6 months I'd been on it, I didn't think there was any harm in stopping it. In an international, multicenter study conducted by Sasha Bernatsky, MD, PhD, of McGill University in Montreal, Quebec, Canada, and colleagues assessing cancer risk in more than 16,000 SLE patients, the overall risk of cancers was found to be only slightly higher than that of the general population; however, the risk of non-Hodgkin lymphoma NHL was higher than expected, with a standardized.